Ambroxol is an antitussive, refers to mucolytics. It is usually prescribed in the presence of a thick, difficult to separate bronchial secretion. The medication has various forms of release, which are used in specific cases.

Release forms and composition

Ambroxol is a Russian-made product published in several forms, which creates additional convenience for its use.

It:

  • pills;
  • injection;
  • solution for inhalation;
  • drops;
  • syrup.

In tablet form contains 30 mg of Ambroxol hydrochloride.

In addition to the active ingredient, Ambroxol tablets consist of the following additional ingredients:

  • corn starch;
  • lactose free;
  • cellulose;
  • silica;
  • magnesium stearate.

In 5 ml of baby syrup Ambroxol contains 15 mg of active ingredient.

Also, this form consists of the following components:

  • flavorings;
  • sodium benzoate;
  • purified water;
  • saccharin sodium;
  • glycerin;
  • menthol;
  • propylene glycol.

In 1 ml of Ambroxol for inhalation contains 7.5 mg of the active ingredient.

In addition, it consists of the following substances:

  • sodium chloride;
  • dihydrate;
  • benzalkonium chloride.

 

The injection solution consists of 15 mg of the active ingredient.

Also injections consist of the following substances:

  • water for injection;
  • sodium chloride;
  • disodium monohydrogen phosphate.

Pharmacological action, pharmacodynamics and pharmacokinetics

Ambroxol refers to mucolytics, has the following pharmacological effect:

  • expectorant as a result of stimulation of motor function;
  • sputum-stimulating;
  • dilutes sputum, reduces its viscosity;
  • improves transportation of bronchial secretion;
  • increases lung surfactant volume;

On a note! As a result of taking Ambroxol, an increase in the secretion of the respiratory organs, removal of sputum from the lungs occur.

Many patients are interested in what cough to take the drug. Ambroxol is known for its broad-colitic effect. If the patient suffers from a dry cough, then the drug has a thinning effect on the thick secret. With a wet cough, the medication improves the elimination of sputum from the lungs.
After ingestion, Ambroxol begins its action in half an hour. If the dosage is observed correctly, then the therapeutic effect is observed within 10 hours. The medicine in the digestive tract is absorbed in a few minutes. After 2 hours, the maximum concentration in the body is observed. The active substance quickly enters the lungs. The medication breaks down by the liver and is excreted by the kidneys within 10 hours.

Why is Ambroxol prescribed

Ambroxol is prescribed by a doctor if the listed diseases are diagnosed:

  • pneumonia;
  • bronchial asthma;
  • tracheitis;
  • obstructive bronchitis;
  • laryngitis;
  • bronchiolitis;
  • pharyngitis;
  • rhinitis;
  • laryngitis;
  • cystic fibrosis;
  • bronchial obstruction.

At what age can children be given

Doctors recommend giving Ambroxol from the neonatal period. Cases of the use of the drug for the treatment of premature babies are also known. Treatment with Ambroxol in children of the first year of life must be carried out strictly under the supervision of a pediatrician. This will help to avoid negative consequences. The tablet form is given if the child does not have difficulty swallowing the tablet. Usually she is prescribed from 6 years.

 

Instructions for use for children and adults

Instructions for use describe different variations of the drug, based on the age of the patient, the type of Ambroxol.

Ambroxol tablets 30 mg

Ambroxol tablets are recommended for cough control in patients over 6 years of age.

The tablet form must be washed down with clean water. Typically, doctors prescribe the drug in the following doses:

  • from 12 years of age - 1 table. twice a day. With intense coughing, it is allowed to take three times;
  • if necessary, it is possible to increase the dosage to 2 tablets. twice;
  • for the pediatric population, the dose of the drug is calculated: 1.2 mg of Ambroxol per 1 kg of weight.

The treatment course is shown individually. Usually it lasts at least 10 days.

Important! It is forbidden to take Ambroxol less than 3 hours before bedtime. This is due to the irritating effect on the cilia of the bronchi, as a result of which the patient may suffer from coughing all night.

Children's cough syrup

The calculation of the dose of Ambroxol in the form of a syrup is based on the age of the children.

  • from 5 years, 5 ml is prescribed 2 times a day (if an acute stage is observed, then an increase in the frequency of administration up to 3 times is possible);
  • from 2 years, a three-time intake of 2.5 ml is recommended;
  • up to 2 years, 2.5 ml is prescribed 2 times a day.

Patients over 12 years of age at the beginning of the disease are prescribed 10 ml 3 times. Further, the dosage is reduced to 5 ml 3 times a day. Usually, therapy lasts for a week. If there is a need for a longer treatment, the dose is reduced by half. It is necessary to drink syrup with a large volume of clean water. This affects the best liquefaction of bronchial secretions, improved withdrawal of sputum.

How to use Ambroxol for inhalation

Ambroxol in a solution for inhalation is allowed to use from the neonatal period. For children over 2 years of age, the dose of the drug is 2 ml, if inhalation is carried out twice a day. The drug is diluted in saline.

 

From 12 years of age, 3 ml of solution is prescribed for inhalation.If necessary, it is possible to increase the procedures up to 3 times per day. Babies in the first year of life are recommended to use 1 ml of Ambroxol. To achieve better hydration of the respiratory system, a 1: 1 dilution is recommended. It is important to ensure that saline has a temperature of at least 36 degrees.

Note! For inhalation, use a nebulizer. Steam inhalers are not suitable for use.

During pregnancy and lactation

The appointment of Ambroxol at the beginning of pregnancy is not shown. In 2, 3 trimesters, the medication is prescribed strictly by a doctor. After assessing the intended benefits to the woman, the potential harm to the fetus. The drug easily overcomes the placental barrier. Therefore, there are known cases of his appointment to the mother, if an unborn baby is diagnosed with accumulation of sputum in the respiratory organs.

On a note! During pregnancy, lactation, it is most advisable to use Ambroxol in the form of inhalation.

During lactation, subject to treatment with Ambroxol, the question of transferring the child to artificial feeding is considered. This is due to the fact that the active component with breast milk penetrates into the children's body.

Drug interaction

The parallel use of Ambroxol with other cough medicines is not recommended. Since this can lead to inhibition of the cough reflex. What contributes to stagnation of sputum, thereby causing a dangerous condition. If there is a need for such a combination, then the combination should be carried out exclusively by a doctor.
Simultaneous administration with antibiotics increases the effect of Ambroxol, improving the symptoms of respiratory infection, and enhances the penetration of the active component of the antibacterial drug into the bronchi.

Contraindications and side effects

Ambroxol administration is not indicated if:

  • hypersensitivity to the active substance;
  • insufficient digestive enzymes;
  • weak cough reflex;
  • impaired transport of mucus;
  • renal failure;
  • serious liver pathologies;
  • gastric ulcer.

 

In these situations, it is advisable to replace the internal use of Ambroxol with inhalation.
Most often, the drug is easily tolerated by patients.

But the instructions for use indicate the possibility of developing the following side effects:

  • rashes on the skin;
  • itching
  • puffiness of the skin;
  • lowering blood pressure;
  • nausea
  • vomiting
  • diarrhea
  • increased nervous excitability;
  • hypersensitivity of the skin;
  • dry mucous membranes.

If these side effects occur, discontinuation of Ambroxol is necessary. If an overdose has occurred, then digestive system problems may develop, and the appearance of nervous excitability is possible. In this case, gastric lavage should be carried out, activated charcoal should be taken.

Analogs

The following drugs belong to Ambroxol analogs by active component:

  • Lazolvan;
  • Flavamed;
  • Ambrobene
  • Abrol;
  • Mucolvan;
  • Halixol;
  • Parallen;
  • Ambroham;
  • Bronchosol;
  • Ambrosan
  • Ambrolan;
  • Bronchial.

 

In addition, there are analogues in the group. They have a similar effect, but differ in side effects.

These include:

  • Mucolyc;
  • ACC;
  • Pulmobriz;
  • Salbroxol;
  • Langes;
  • Bromhexine;
  • Cysteine;
  • Acetal;
  • Solvin;
  • Bronchobos
  • Ascoril.

 

Often, a question arises for parents: Bromhexine or Ambroxol, which is better. It should be decided with the attending physician, since it is necessary to be guided by the clinical picture of the patient, the severity of the disease. The famous pediatrician Komarovsky with bronchitis and pneumonia recommends the use of Ambroxol, which more quickly and effectively eliminates sputum from the respiratory tract. If the patient suffers from epileptic seizures, convulsions, then the drug is best replaced with Bromhexine.

Ambroxol is known as a drug of wide mucolytic effect. It has various forms of release, which allows it to be assigned in different situations and for different age groups.

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